Toxicological and safety evaluation of Nigella sativa lipid and volatile fractions in streptozotocin induced diabetes mellitus
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چکیده
منابع مشابه
Effect of Nigella sativa fixed and essential oils on antioxidant status, hepatic enzymes, and immunity in streptozotocin induced diabetes mellitus
BACKGROUND Nigella sativa fixed (NSFO) and essential (NSEO) oils have been used to treat diabetes mellitus and its complications. Present study was undertaken to explore and validate these folkloric uses. METHODS Sprague dawley rats having streptozotocin (STZ) induced diabetes mellitus were used to assess the role of NSFO and NSEO in the management of diabetes complications. Parameters invest...
متن کاملNigella sativa Fixed and Essential Oil Supplementation Modulates Hyperglycemia and Allied Complications in Streptozotocin-Induced Diabetes Mellitus
In the recent era, diabetes mellitus has emerged as one of the significant threats to public health and this situation demands the attention of the researchers and allied stakeholders. Dietary regimens using functional and nutraceutical foods are gaining wide range of acceptance and some traditional medicinal plants are of considerable importance. The main objective of this instant study was to...
متن کاملHypoglycemic Effects of Nigella Sativa Extract and Endurance Training in Streptozotocin Induced Diabetic Rats
Objective: Diabetes is a common disease and its prevalence rate is rapidly increasing. Aim of present study was to review the hypoglycemic effects of Nigella sativa (N.sativa) extract and endurance training in streptozotocin induced diabetic rats. Materials and Methods: In this experimental research from 50 streptozotocine induced diabetic rats, 32 rats with more than 300 mg/dL fasting blood g...
متن کاملThe Antidiabetic Activity of Nigella sativa and Propolis on Streptozotocin-Induced Diabetes and Diabetic Nephropathy in Male Rats
This study was conducted to compare the ameliorative effect of Nigella sativa and propolis methanol extract on streptozotocin-induced diabetic male rats and treating diabetic nephropathy. Forty male Albino rats were divided into four groups; the first group was the negative control fed standard diet. The other 30 rats were injected with streptozotocin to induce diabetes by a single intravenous ...
متن کاملPterocarpus santalinus ameliorates streptozotocin-induced diabetes mellitus via anti-inflammatory pathways and enhancement of insulin function
Objective(s): Morbidity and mortality due to diabetes mellitus (DM) result in exorbitant psycho-economical costs, so there is a strong need to create new strategies and drugs for controlling DM. The aim of the current study was to investigate the anti-diabetic effect of the aqueous extract of Pterocarpus santalinus on streptozotocin (STZ)-induced DM as compared to glus...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Tropical Disease
سال: 2014
ISSN: 2222-1808
DOI: 10.1016/s2222-1808(14)60709-x